Medical Health Cluster

Artículos destacados

Paxlovid Reduces Risk of COVID Death by 79% in Older Adults: Study

The antiviral drug Paxlovid appears to reduce the risk of dying from COVID-19 by 79% and decrease hospitalizations by 73% in at-risk patients who are ages 65 and older, according to a new study published in The New England Journal of Medicine. The pill, which is a combination of the drugs nirmatrelvir and ritonavir, […]

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Global Orphanhood Associated with COVID-19

Summary Globally, millions of children have become orphans during the COVID-19 pandemic. Orphanhood increases the likelihood of poverty, abuse, delayed development, mental health challenges, reduced access to education, and institutionalization. The number of children in urgent need continues to grow, a collaboration of 13 international organizations reveals. Global Orphanhood Associated […]

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HIV and Sexually Transmitted Infections Among Persons with Monkeypox

Summary What is already known about this topic? In the current global monkeypox outbreak, HIV infection and sexually transmitted infections (STIs) are highly prevalent among persons with monkeypox. What is added by this report? Among 1,969 persons with monkeypox in eight U.S. jurisdictions, 38% had HIV infection, and 41% had […]

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Treatment of Clostridioides difficile Infection

Guideline title ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections Release date May 18, 2021 Prior version 2013 Developer American College of Gastroenterology (ACG) Funding source ACG Target population Adults with suspected or diagnosed Clostridioides difficile infection (CDI) Major recommendations Initial CDI should be treated with vancomycin or fidaxomicin (strong recommendation; moderate-quality evidence). Metronidazole may be considered […]

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Paxlovid Expiration Dates Extended

Expiration dates have been extended from 9 months after manufacture to 12 months for 4 lots of the COVID-19 antiviral therapy Paxlovid, which consists of copackaged nirmatrelvir tablets and ritonavir tablets. The lot numbers and original expiration dates are listed on the FDA website. The nirmatrelvir-ritonavir lots were manufactured before the FDA […]

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A Better Treatment Option for Drug-Resistant Tuberculosis

Safe, effective treatment options are urgently needed for those with tuberculosis caused by drug-resistant Mycobacterium tuberculosis. In a recent study in South Africa, the combination of bedaquiline, pretomanid, and linezolid (1200 mg linezolid daily; BPL 1200) for 26 weeks yielded a microbiologic cure rate over 90%, but with significant linezolid toxicity […]

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JACC: Case Reports Explores Acute Myocarditis in Monkeypox Patient

With the recent outbreak of Monkeypox virus infection in nonendemic countries like the U.S., Australia, Spain, UK, etc., the world’s attention has been directed to the clinical manifestations of this disease. A new case published in JACC: Case Reports highlights “cardiac involvement as a potential complication” associated with the disease. The case […]

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