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Vaccines

Hallada la posible causa de la Covid-19 persistente

Un nuevo estudio realizado por investigadores del National Jewish Health (Estados Unidos) y publicado en la revista científica ‘American Journal of Respiratory and Critical Care Medicine’ ha arrojado luz sobre la causa de los síntomas de Covid-19 persistente que podría ayudar a los expertos a empezar a desarrollar tratamientos. “No hay ninguna […]

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Questions Remain About Who Will Get Monoclonal Antibodies for COVID-19 Preexposure Prophylaxis

Every day for weeks this past fall, Brian Koffman, MD, would Google “AZD7442, AZD7442, AZD7442.” He finally hit pay dirt December 8, when he discovered that the US Food and Drug Administration had authorized AstraZeneca’s long-acting monoclonal antibody combination, AZD7442 (Evusheld), for COVID-19 preexposure prophylaxis in adults and children at least 12 years […]

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Vaccinated With Prior Infection Most Protected During Delta Wave

Following the emergence of the Delta variant, individuals who had a prior COVID-19 infection with or without vaccination had lower case rates than those who were vaccinated alone, data from California and New York found. “Infection-derived protection was higher after the Delta variant became predominant, a time when vaccine-induced immunity […]

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Omicron (B.1.1.529) – variant of concern – molecular profile and epidemiology: a mini review

Abstract Recently a new variant of SARS-CoV-2 was reported from South Africa. World Health Organization (WHO) named this mutant as a variant of concern – Omicron (B.1.1.529) on 26th November 2021. This variant exhibited more than thirty amino acid mutations in the spike protein. This mutation rate is exceeding the […]

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Poor Memory and Attention Persists Months After Mild COVID Recovery

Long-COVID is now recognised and accepted as a clinical entity with fatigue, cough, and headache being common symptoms. The National Institute for Health and Care Excellence (NICE) offers guidance for the management of long-COVID, with the NHS providing specialist long-COVID clinics. In December 2021 the Office for National Statistics (ONS) reported that 1 in 5 […]

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10 key global health moments from 2021

It has been a year of colossal efforts in global health. Countries battled COVID-19, which claimed more lives in 2021 than in 2020, while struggling to keep other health services running. Health and care workers have borne the lion’s share of these efforts but often received little recognition or reward. Life-saving COVID-19 vaccines, tests and treatments were […]

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Which COVID Outpatient Therapy Should Clinicians Reach For?

Due to the Omicron variant and the short supply of COVID therapeutics, NIH recommends certain therapies over others for patients at high risk of progressing to severe COVID, said federal officials on a call with clinicians Wednesday. In order of preference, clinicians should use the oral antiviral nirmatrelvir-ritonavir (Paxlovid), the monoclonal […]

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Antibody Response and Variant Cross-Neutralization After SARS-CoV-2 Breakthrough Infection

Breakthrough infections after vaccination against SARS-CoV-2 are increasingly reported, possibly due to waning of vaccine-induced antibody levels.1 Moreover, emerging variants of concern with diminished susceptibility to vaccine-induced antibodies are responsible for most new cases.2,3 Studies have focused on determining the rate of vaccine breakthrough based on antibody levels after standard vaccination practices.4,5 We […]

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Early Tracheostomy for Managing ICU Capacity During the COVID-19 Outbreak

Background During the first wave of the COVID-19 pandemic, shortages of ventilators and ICU beds overwhelmed health care systems. Whether early tracheostomy reduces the duration of mechanical ventilation and ICU stay is controversial. Research Question Can failure-free day outcomes focused on ICU resources help to decide the optimal timing of tracheostomy […]

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