Medical Health Cluster


Estimated Effectiveness of JYNNEOS Vaccine in Preventing Mpox: A Multijurisdictional Case-Control Study — United States, August 19, 2022–March 31, 2023

Summary What is already known about this topic? Real-world vaccine effectiveness (VE) estimates for JYNNEOS vaccine against monkeypox (mpox) are limited. To date, no VE estimates by route of administration or for immunocompromised persons have been published. What is added by this report? In this study, adjusted VE was 75% […]

Read More

Neonatal Monkeypox Virus Infection

The ongoing monkeypox outbreak was recently declared to be a Public Health Emergency of International Concern by the World Health Organization.1 Young children are at risk for severe disease; therefore, early recognition and prompt treatment are important.2 We report a case of perinatally acquired monkeypox virus infection and adenovirus coinfection in […]

Read More

Two Cases of Monkeypox-Associated Encephalomyelitis — Colorado and the District of Columbia, July–August 2022

Summary What is already known about this topic? Monkeypox virus (MPXV) typically causes a febrile illness with lymphadenopathy and a diffuse vesiculopustular rash; neurologic complications are rare. The current monkeypox outbreak differs clinically and epidemiologically from previous outbreaks, and little is known about potential associated neurologic complications. What is added by […]

Read More

Disinfecting Home and Other Non-Healthcare Settings

Purpose of Home Disinfection People with monkeypox who do not require hospitalization may be isolated at home. Monkeypox spreads between people through direct contact with an infectious rash, body fluids, or by respiratory secretions during prolonged, face-to-face contact. Transmission of Monkeypox virus is possible from the onset of the first symptoms until […]

Read More

Monkeypox Link to Encephalitis ‘Needs Further Investigation’

Scientists have reported preliminary evidence that monkeypox might lead to severe neurological complications including encephalitis and seizure. Other nonspecific neurological conditions, including confusion, headache, and myalgia have also been linked to the disease, according to the research led by University College London (UCL). Despite evidence of nervous system involvement associated […]

Read More

HIV and Sexually Transmitted Infections Among Persons with Monkeypox

Summary What is already known about this topic? In the current global monkeypox outbreak, HIV infection and sexually transmitted infections (STIs) are highly prevalent among persons with monkeypox. What is added by this report? Among 1,969 persons with monkeypox in eight U.S. jurisdictions, 38% had HIV infection, and 41% had […]

Read More