With the recent outbreak of Monkeypox virus infection in nonendemic countries like the U.S., Australia, Spain, UK, etc., the world’s attention has been directed to the clinical manifestations of this disease. A new case published in JACC: Case Reports highlights “cardiac involvement as a potential complication” associated with the disease. The case […]
The risk of myocarditis after immunization with mRNA-based vaccines against SARS-CoV-2 raised concerns when it came to light in early 2021. But as report after report showed such cases to be rare and usually mild and self-limited, focus has turned to the “how and why.” The mechanism linking the BNT162b2 (Pfizer-BioNTech) and especially mRNA-1273 (Moderna) […]
The first large population study to investigate the association between different COVID-19 vaccines types and cardiac effects and adverse events shows a small increase in the risk for acute myocarditis with both the mRNA-based vaccines and — in what may a first in the literature — an adenovirus-vector vaccine. The […]
Myocarditis is an inflammatory disease of the myocardium with a wide range of clinical presentations, from subtle to devastating. It usually manifests in an otherwise healthy person and can result in rapidly progressive (and fatal) heart failure and arrhythmia. Recently, myocarditis has been associated with COVID-19 and, to a much […]
Two large studies confirm low overall risk for myocarditis, highest risk in young men, and mild cases in most. Defining the frequency and severity of myocarditis after vaccination has great public health importance. Two retrospective Israeli studies have addressed this issue, one in a large healthcare organization and the other […]
Practice Essentials Myocarditis is an inflammatory disease of the myocardium with a wide range of clinical presentations, from subtle to devastating. The image below depicts numerous lymphocytes with associated myocyte damage. Myocarditis. Hematoxylin and eosin staining. Low power. This image shows numerous lymphocytes with associated myocyte damage. Photo courtesy of […]
While cases of pericarditis or myocarditis temporally linked to COVID-19 vaccination remain rare, they may happen more often than reported, according to a large review of electronic medical records (EMR). They also appear to represent two “distinct syndromes,” George Diaz, MD, Providence Regional Medical Center Everett, Everett, Washington, told theheart.org | Medscape Cardiology. Myocarditis typically […]
Further details from multiple cases of myocarditis linked to the Pfizer and Moderna mRNA COVID vaccines have been described in recent papers in the medical literature. The cases appear to occur almost exclusively in males and most often in younger age groups. While symptoms and signs of myocarditis mostly resolved with a […]
The US Food and Drug Administration (FDA) is adding a warning to the fact sheets for the Pfizer/BioNTech and Moderna mRNA COVID-19 vaccines as medical experts continue to investigate cases of heart inflammation, which are rare but are more likely to occur in young men and teen boys. Doran Fink, MD, […]
