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Large Cohort Study Finds Possible Association Between Postural Orthostatic Tachycardia Syndrome and COVID-19 Vaccination but Far Stronger Link With SARS-CoV-2 Infection

Shortly after COVID-19 vaccines first became available, Tae Chung, MD, noticed something unusual at the Johns Hopkins Postural Orthostatic Tachycardia Syndrome (POTS) program, which he directs. Seven patients newly diagnosed with POTS were either medical students or physicians. They had no recent history of SARS-CoV-2 infection, which, research has suggested, […]

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CDC Identifies Two Monkeypox Strains in US; Provides Updates on Investigation

At least two strains of monkeypox are currently circulating in the United States, officials from the Centers for Disease Control and Prevention (CDC) said Friday. Most cases in the United States involve the same strain that has been spreading in the United Kingdom and Europe, but investigators have also detected […]

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Man Who Received First Modified Pig Heart Transplant Dies

David Bennett Sr, the 57-year-old patient with terminal heart disease who became the first person to receive a genetically modified pig heart, has died. He passed away yesterday, according to a statement from the University of Maryland Medical Center (UMMC), Baltimore, where the transplant was performed. Bennett received the transplant on January 7 and […]

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Structures of the Omicron Spike trimer with ACE2 and an anti-Omicron antibody

The SARS-CoV-2 Omicron variant has become the dominant infective strain. We report the structures of the Omicron spike trimer on its own or in complex with ACE2 or an anti-Omicron antibody. Most Omicron mutations are located on the surface of the spike protein, which change binding epitopes to many current […]

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Un estudio con 680 sanitarios vacunados refleja que 679 conservaban anticuerpos a los seis meses

Un estudio en 680 sanitarios del área de salud Valladolid Oeste inoculados con dos dosis de la vacuna contra la COVID-19 ha puesto sobre la mesa que todos generaron anticuerpos, sólo uno no los tenía a los seis meses y sólo el 1,2%, ocho de ellos, volvieron a contagiarse. Tal y como explican desde el Hospital Río Hortega (Valladolid), […]

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COVID-19 Patients Face Risks After Hospital Discharge

People face substantially higher risks of health problems in the months after being discharged from the hospital following a bout of COVID-19, researchers in England found. Comparing 24,673 COVID-19 patients who survived at least a week after hospital discharge and 123,362 similarly aged people in the general population, they found […]

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Molnupiravir, de MSD, eficaz en el tratamiento contra la variante Ómicron

MSD y RidgebackBiotherapeutics han anunciado que molnupiravir, el medicamento antiviral oral contra la Covid-19 que están desarrollando, se muestra activo in vitro frente a la variante Ómicro del SARS-CoV-2, causante de la última ola de contagios en el mundo. Los hallazgos se han publicado en seis estudios preclínicos. “Estos hallazgos de múltiples estudios in vitro independientes que muestran de manera […]

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Second ground-breaking antiviral to be deployed to country’s most vulnerable

PF-07321332+ritonavir will be made available to those with weakened immune systems from Thursday 10 February Innovative treatment reduced the risk of hospitalisation or death by 88% in clinical trials The UK has procured more antivirals per head than any other country in Europe with over 4.98m courses ordered so far […]

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What’s the Benefit of a Fourth COVID Vaccine?

Experts say additional boosters could provide diminishing returns Once, twice, and now three times, many people in the U.S. have rolled up their sleeves to get vaccinated against COVID-19. But as daily infections break records and hospitals across the country near capacity during the Omicron surge, many people have raised […]

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