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Immunity

COVID-19 insights: Waning immunity will impact long-range forecasts

The latest takeaways from IHME: Regional updates: China continues the zero-COVID strategy and reports no increase in cases. South Africa may be reaching a peak of the BA.4/BA.5 winter surge. The United States is experiencing an increase in Omicron cases – likely due to behavioral changes, and possibly due to […]

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Latest COVID Subvariants Create New Waves, Evade Immunity

As COVID-19 cases and hospitalizations begin to increase again in the U.S., public health officials are monitoring several new Omicron subvariants that are contributing to the case numbers. In some parts of the U.S., a spinoff of the BA.2 subvariant called BA.2.12.1 is the main culprit. In other countries, Omicron […]

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Omicron Sublineages Evade Immunity From Past Infection

A South African study based on blood samples found that the BA.4 and BA.5 sub-lineages of Omicron were more likely to evade antibodies produced by previous Omicron infections than the immunity provided by vaccinations. Scientists took blood samples from 39 people infected with Omicron, with 24 people not vaccinated and […]

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‘Uptick’ in COVID Cases Among Older People in February Could Stem from Waning Immunity

Cases of COVID-19 show signs of rising among the over-55s, raising the possibility that the pandemic could be prolonged by the spread of the BA.2 sub-lineage of the Omicron variant, a study has suggested. Increased socialising and waning immunity after vaccination could be behind the development, scientists led by a team […]

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COVID-19: Why Are We Ignoring Infection-Acquired Immunity?

Antibodies derived from natural infection with COVID-19 are more abundant and more potent – at least 10 times more potent – than immunity generated by vaccination alone, according to a study from Oregon Health & Science University (OHSU) in Portland, US, published on January 25. Three days later, the US Centres for Disease […]

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New Study Shows Natural Immunity to COVID Has Enduring Strength

It’s a matter of quality, not quantity. That’s the gist of a new Israeli study that shows that unvaccinated people with a prior SARS-CoV-2 infection create antibodies that are more effective in the long run compared with others who were vaccinated but never infected. “While the quantity of antibodies decreases with […]

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Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity?

Many nations are pursuing the rollout of SARS-CoV-2 vaccines as an exit strategy from unprecedented COVID-19-related restrictions. However, the success of this strategy relies critically on the duration of protective immunity resulting from both natural infection and vaccination. SARS-CoV-2 infection elicits an adaptive immune response against a large breadth of […]

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Vaccines beat natural immunity in fight against COVID-19

The best protection against COVID-19? Getting vaccinated, not waiting for illness to create natural immunity, says infectious disease expert Anna Durbin. A common reason cited for not getting vaccinated against COVID-19—especially among the young and healthy—is “I trust my immune system” or some variation of that line. The same goes […]

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