Efficacy of Portable Air Systems in Hospital Rooms

Transmission of SARS-CoV-2 from patients to healthcare workers has occurred despite the use of personal protective equipment (PPE). Researchers in the U.K. posited that portable systems combining high-efficiency particulate air (HEPA) filtration with ultraviolet (UV) light could provide additional safety by removing viral particles from the air. They studied two multi-bed units dedicated to patients with COVID-19. Nucleic acids were extracted from air samples in medium (1–4 µm) and large (>4µm)–sized particulate fractions and from the filter (<1 µm), and RT-PCR was performed to identify viruses, bacteria, and fungi.

In a six-bed room with the air system off, SARS-CoV-2 RNA was detected in medium and large aerosol fractions every day of testing for 1 week. When a portable HEPA/UV system was turned on in the same room for the second week, no SARS-CoV-2 RNA was detected. In a four-bed room in an intensive care unit, limited evidence of SARS-CoV-2 RNA was seen during the first week (when the system was off), but SARS-CoV-2 RNA was detected in a single sample during the week when the system was on. For both units, the total number of bioaerosol detections when the system was off was significantly higher than when it was on.