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Trending Clinical Topic: Coffee

The worldwide popularity of coffee means that any research into health concerns or benefits is of widespread interest. New findings regarding potential protective effects and risks have once again resulted in the beverage becoming a top trending clinical topic. A new study in Kidney International Reports and material presented at this spring’s American College […]

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NIH launches clinical trial of three mRNA HIV vaccines

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched a Phase 1 clinical trial evaluating three experimental HIV vaccines based on a messenger RNA (mRNA) platform—a technology used in several approved COVID-19 vaccines. NIAID is sponsoring the study, called HVTN 302, […]

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They built a smarter approach to Covid clinical trials. Now they want to do the same for other diseases

Agroup of scientists who did more than perhaps any other to test new treatments for Covid, including establishing that the steroid dexamethasone can save lives, is now turning its focus to the rest of medicine. The first step, announced today: a partnership with the Paris-based drug giant, Sanofi. Sanofi will […]

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Clinical Spectrum of SARS-CoV-2 Infection

Patients with SARS-CoV-2 infection can experience a range of clinical manifestations, from no symptoms to critical illness. This section of the Guidelines discusses the clinical presentation of SARS-CoV-2-infected individuals according to illness severity. In general, adults with SARS-CoV-2 infection can be grouped into the following severity of illness categories. However, […]

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Clinical Trends Among U.S. Adults Hospitalized with COVID-19, March-December 2020

Abstract Background The COVID-19 pandemic has caused substantial morbidity and mortality. Objectives To describe monthly demographic and clinical trends among adults hospitalized with COVID-19. Design Pooled cross-sectional. Setting 99 counties within 14 states participating in the Coronavirus Disease 2019-Associated Hospitalization Surveillance Network (COVID-NET). Patients U.S. adults (aged ≥18 years) hospitalized with laboratory-confirmed COVID-19 during March […]

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New SARS-CoV-2 Variants Clinical, Public Health, and Vaccine Implications

Across the world, there are multiple variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19). SARS-CoV-2 variants have been classified by the Centers for Disease Control and Prevention (CDC) as variants of interest, variants of concern, and variants of high consequence. Three […]

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