Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity

Key Points Question  Does prior COVID-19 vaccination reduce hospitalizations for COVID-19, and among patients hospitalized for COVID-19, does prior vaccination reduce disease severity? Findings  In a case-control study that included 4513 hospitalized adults in 18 US states, hospitalization for a COVID-19 diagnosis compared with an alternative diagnosis was associated with an adjusted […]

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Association Between K–12 School Mask Policies and School-Associated COVID-19 Outbreaks — Maricopa and Pima Counties, Arizona, July–August 2021

CDC recommends universal indoor masking by students, staff members, faculty, and visitors in kindergarten through grade 12 (K–12) schools, regardless of vaccination status, to reduce transmission of SARS-CoV-2, the virus that causes COVID-19 (1). Schools in Maricopa and Pima Counties, which account for >75% of Arizona’s population (2), resumed in-person […]

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Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19A Meta-analysis

The WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group Article Information Key PointsQuestion  Is administration of IL-6 antagonists associated with 28-day all-cause mortality in patients hospitalized for COVID-19?Findings  This prospective meta-analysis of 27 randomized trials included 10 930 patients, of whom 2565 died by 28 days. The 28-day all-cause mortality was […]

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