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Antivirals

COVID Antivirals Appear to Hold Up Against BA.2

While two monoclonal antibody combinations showed neutralizing activity against the Omicron subvariant BA.2, both required substantially higher concentrations to produce a response in patients with COVID-19, Japanese researchers said, while antivirals appeared to be less affected. Casirivimab/imdevimab (REGEN-COV) and tixagevimab/cilgavimab (Evusheld) inhibited BA.2, but the titer of monoclonal antibodies “required […]

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Antivirals against SARS-CoV-2 by autumn?

An over ambitious target that risks forced errors The UK government has launched a covid-19 antivirals taskforce with the aim of deploying drugs for home treatment by autumn this year.1 The description suggests that the government wants direct acting orally administered drugs that reduce replication and help eliminate SARS-CoV-2 from the […]

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