Medical Health Cluster

antibodies

In Rheumatic Disease, mRNA COVID-19 Vaccination More Likely Than J&J Shot to Generate Antibodies

(Reuters Health) – Patients with rheumatic and musculoskeletal diseases may be less likely to mount an antibody response to the Johnson and Johnson (J&J) COVID-19 vaccine compared with those who get an mRNA-based vaccine, a new study suggests. Data from a prospective cohort of 1,039 patients with rheumatic and musculoskeletal […]

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Can a Subcutaneous Shot of Monoclonal Antibodies Prevent COVID-19?

An injected monoclonal cocktail given to household contacts of patients with COVID-19 was 81% effective. Postexposure prophylaxis with immunoglobulins has been the standard of care for many infectious diseases; thus, an effective immunoglobulin preparation for COVID-19 would provide a powerful new public health approach to controlling the current pandemic. Researchers […]

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Injectable Monoclonal Antibodies Prevent COVID-19 in Trial

A combination of two monoclonal antibodies given as a subcutaneous injection prevented COVID-19 in patients at a high risk of infection due to household exposure, according to results of a randomized, double-blind, placebo-controlled clinical trial published online August 4 in the New England Journal of Medicine. The cocktail of the monoclonal antibodies casirivimab and […]

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INO-4800 DNA Vaccine Induces Neutralizing Antibodies and T cell Activity Against Global SARS-CoV-2 Variants

Abstract Global surveillance has identified emerging SARS-CoV-2 variants of concern (VOC) associated with broadened host specificity, pathogenicity, and immune evasion to vaccine induced immunity. Here we compared humoral and cellular responses against SARS-CoV-2 VOC in subjects immunized with the DNA vaccine, INO-4800. INO-4800 vaccination induced neutralizing antibodies against all variants […]

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Neutralizing the Virus: A Focus on SARS-CoV-2–Specific Monoclonal Antibodies

Educational Impact Challenge The goal of this activity is to increase clinicians’ knowledge and understanding of how neutralizing monoclonal antibodies function to both treat patients with COVID-19 and prevent disease in others.  Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after […]

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Covid-19: Eight in 10 Wuhan residents with antibodies had no symptoms, finds study

More than three quarters of Wuhan residents who tested positive for SARS-CoV-2 antibodies had experienced no covid-19 symptoms and just under half developed long lasting neutralising antibodies, show results from the first long term seroprevalence study from the epicentre of the outbreak in China.1 Researchers tested 9542 people from 3556 […]

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