Medical Health Cluster

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COVID Antivirals Appear to Hold Up Against BA.2

While two monoclonal antibody combinations showed neutralizing activity against the Omicron subvariant BA.2, both required substantially higher concentrations to produce a response in patients with COVID-19, Japanese researchers said, while antivirals appeared to be less affected. Casirivimab/imdevimab (REGEN-COV) and tixagevimab/cilgavimab (Evusheld) inhibited BA.2, but the titer of monoclonal antibodies “required […]

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Antiviral Drug Combo Is Highly Effective Against SARS-CoV-2 

Researchers have identified a powerful combination of antivirals to treat COVID-19. Combining the drug brequniar with remdesivir or molnupiravir — both approved by the U.S. Food and Drug Administration for emergency use — inhibited the SARS-CoV-2 virus in human respiratory cells and in mice, according to a new study led […]

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