Medical Health Cluster

13 junio, 2022

Trending Clinical Topic: Coffee

The worldwide popularity of coffee means that any research into health concerns or benefits is of widespread interest. New findings regarding potential protective effects and risks have once again resulted in the beverage becoming a top trending clinical topic. A new study in Kidney International Reports and material presented at this spring’s American College of Cardiology (ACC) 2022 Scientific Session offer coffee cravers a reason to smile (see Infographic).

Researchers recently found that participants who drank any quantity of coffee every day had an 11% lower risk for acute kidney injury than those who don’t drink coffee. The study included more than 14,000 adults from the Atherosclerosis Risk in Communities (ARIC) study. Among the participants, 17% drank more than three cups daily, 23% drank two to three cups daily, 19% drank one cup daily, 14% drank less than one cup daily, and 27% never drank coffee. Mean age was about 54 years for the cohort. During a median follow-up of 24 years, almost 1700 acute kidney injury incidents were reported. Results showed that increased coffee drinking was linked with reduced acute kidney injury risks, as indicated by the following data:

  • Reference: Never, P = .003
  • Three cups daily: hazard ratio (HR), 0.83 (95% CI, 0.71-0.96)
  • Two to three cups daily: HR, 0.83 (95% CI, 0.72-0.95)
  • One cup daily: HR, 1.08 (95% CI, 0.94-1.24)
  • Less than 1 cup daily: HR, 0.92 (95% CI, 0.79-1.08)

At ACC 2022, three analyses using the prospective UK Biobank cohort found that coffee may be cardioprotective. Participants were on average in their late 50s. Those who reported regular daily intake of two to three cups of coffee had significantly reduced risks for cardiovascular disease (CVD), coronary heart disease (CHD), heart failure, arrhythmias, and death from any cause over 10 years (P < .01 for all endpoints). The HRs and 95% CIs were:

  • CVD: HR, 0.91; 95% CI, 0.88-0.94
  • CHD: HR, 0.90; 95% CI, 0.87-0.93
  • Heart failure: HR, 0.85; 95% CI, 0.81-0.90
  • Arrhythmia: HR, 0.92; 95% CI, 0.88-0.95
  • Death from any cause: HR, 0.86; 95% CI, 0.83-0.90

Recent news wasn’t all good for coffee and heart health concerns. A new population-based, cross-sectional study found that espresso consumption is associated with higher total cholesterol levels. The results were published online in the journal Open Heart. The findings indicate that drinking three to five cups of espresso each day was significantly linked with greater serum total cholesterol by 0.16 mmol/L (95% CI, 0.07-0.24) for men and by 0.09 mmol/L (95% CI, 0.01-0.17) for women, compared with participants who did not drink espresso daily. Consumption of six or more cups of plunger/boiled coffee each day (compared with none) was linked with elevated serum total cholesterol levels by 0.23 mmol/L (95% CI, 0.08-0.38) for men and 0.30 mmol/L (95% CI, 0.13-0.48) for women. Serum total cholesterol increased 0.11 mmol/L (95% CI, 0.03-0.19) in women who drank six or more cups of filtered coffee per day, but no increase was seen in men who drank this amount and type of coffee.

Still, when it comes to interpreting this piece of cholesterol and coffee data, experts say not to overreact. “I don’t think that the findings in this paper are necessarily enough to change any advice about coffee,” said David Kao, MD, an associate professor medicine at the University of Colorado Anschutz Medical Campus in Denver, in commenting on the findings. “If one has to choose between this study, which would suggest to drink less coffee to maintain low cholesterol, and the others, which would suggest that increasing coffee consumption might reduce risk for multiple kinds of CVD, one should choose the latter,” Kao concluded.

Choosing coffee is a daily decision for many, and recent studies are not likely to discourage that choice any time soon. News about possible benefits for the kidneys, heart, and overall mortality helped make the drink the top trending topic of the week.

Créditos: Comité científico Covid

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